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教授
李磊
作者: 发布日期:2024-09-23



基本信息:

姓名:李磊

职称:教授

学历:博士

电子信箱:llee2005@163.com

出生年月:1986.06

研究方向功能有机分子绿色合成可见光导的绿色化学转化多肽及蛋白分子的氮端修饰

学习及工作经历

2023.01. -          聊城大学                                             教授

2020.08. - 2022.12.   安徽大学                                             副教授

2017.09. - 2020.07.   南京大学                                             博士

2013.07. - 2017.08.   南方科技大学                                      研究助理

2009.09. - 2012.06.   华东师范大学                                            硕士

2005.09. - 2009.06.  阜阳师范大学                                           学士

个人简介李磊,教授硕士生导师,山东省泰山学者青年专家,聊城大学光岳学者特聘教授。主要研究方向为有机功能分子转化和可见光导的光化学反应。近年来,研究工作集中于惰性键活化、可见光促进的官能团转化以及功能有机分子(光、电、生物活性分子)结构性质研究,发展了温和条件下中/大环分子构建新方法,开发了可见光诱导的碳-碳键活化新体系,探索功能有机分子的结构后修饰,揭示惰性有机分子催化转化反应机理。在高水平期刊Sci. Adv.Nat. Commun.Org. Lett.Chin. Chem. Lett.Mat. Res. Lett.Chem. Commun.Org. Chem. Front.等发表论文40余篇。主持国家自然科学基金青年项目、聊城大学高层次人才启动基金、企业合作项目各一项,参与多个国家自然科学基金项目的研究工作,连续指导三届全国大学生化学实验创新设计大赛获赛区一等奖一项、二等奖两项。

发表论文:

  1. Lei Li, Zhong-Liang Li, Qiang-Shuai Gu, Na Wang, Xin-Yuan Liu*, A remote C–C bond cleavage–enabled skeletal reorganization: Access to medium-/large-sized cyclic alkenes, Sci. Adv. 2017, 3, e1701487.

  2. Lei Li, Zhong-Liang Li, Fu-Li Wang, Zhen Guo, Yong-Feng Cheng, Na Wang, Chao Fang, Jingjiang Liu, Chunhui Hou, Bin Tan, Xin-Yuan Liu*, Remote Radical Aryl Migration Enables Diversity-Oriented Synthesis of Structurally Diverse Medium/Macro- or Bridged-Rings, Nat. Commun. 2016, 7, 13852.

  3. Hao Jia, Xuening Sun, Xinmiao Meng, Min Wu, Aisen Li, Miao Yang , Chengyuan Wang*, Jiaxiang Yang*, Kai Wang, Qian Li*, Lei Li*, Developing piezochromic luminescent materials via regioselective cyanation of naphthalimidecyanostilbene derivatives, Mater. Chem. Front., 2024, 8, 3064.

  4. Zhenzhen Gao*; Xiaoming Zhou; Baoshen Nie; Hanchong Lu; Xiaotong Chen; Jiahui Wu; Xuekun Wang; Lei Li*, Synthesis of 3,4-Disubstituted Maleimide Derivatives via Phosphine-Catalyzed Isomerization of α-Succinimide-Substituted Allenoates Cascade γ′-Addition with Aryl Imines, Int. J. Mol. Sci. 2024, 25, 6916.

  5. Zhenzhen Gao*,, Xiaoming Zhou, Dandan Liu, Baoshen Nie, Hanchong Lu, Xiaotong Chen, Jiahui Wu, Lei Li*, Xuekun Wang*, Phosphine-Catalyzed γ′-Carbon 1,6-Conjugate Addition of α-Succinimide Substituted Allenoates with Para-Quinone Methides: Synthesis of 4-Diarylmethylated 3,4-Disubstituted Maleimides, Molecules 2024, 29, 2593.

  6. Min Hong*, Juan Wang, Haobin Chen, Jiayu Qi, Qinghong Ji, Xiaoyan Liu, Qiaoli Yue, Lei li*, Shuang Cheng*, Synthesis and biological evaluation of folic acid-rotenol conjugate as a potent targeted anticancer prodrug, Eur. J. Pharmacol. 2024, 970, 176482.

  7. Xinmiao Meng, Lin Wei, Min Wu, Aisen Li, Lei Li*, Kai Wang*, Qian Li*, Resolving multiple emissions of zero-dimensional heterometallic halide hybrid via pressure-triggered antenna effect, Mater. Res. Lett. 2024, 12, 417.

  8. Yan-Rui Zhao , Lei Li, Jun Xuan, Catalyst-Free, Multicomponent Reaction of Iodonium Ylides, Nitrosoarenes, and Olefins for the Synthesis of Isoxazolidine Derivatives, Synlett 2023, 34, 2022.

  9. Yan-Rui Zhao, Lei Li*, Jun Xuan*, Direct Synthesis of Indolines via Cyclization of Tertiary Aryl Amines with Iodonium Ylides under Sole Visible Light Irradiation, Adv. Synth. Catal. 2023, 365, 110.

  10. Hai-Bing Ye, Xu-Yu Zhou, Lei Li*, Xiang-Kui He, Jun Xuan*, Photochemical Synthesis of Succinic Ester-Containing Phenanthridines from Diazo Compounds as 1,4-Dicarbonyl Precursors, Org. Lett. 2022, 24, 6018.

  11. Bao-Gui Cai, Qian Li, Qiong Zhang*, Lei Li*, Jun Xuan*, Synthesis of trisubstituted hydroxylamines by visible light-promoted multicomponent reaction, Org. Chem. Front. 2021, 8, 5982.

  12. Shuang-Jing Zhou, Bao-Gui Cai, Chun-Xia Hu, Xu Cheng, Lei Li,* Jun Xuan,* Visible light and base promoted O-H insertion/cyclization of para-quinone methides with aryl diazoacetates: An approach to 2,3-dihydrobenzofuran derivatives, Chin. Chem. Lett. 2021, 32, 2577.

  13. Juan Lu, Lei Li,* Xiang-Kui He, Guo-Yong Xu,* Jun Xuan,* Visible Light-Promoted Sulfoxonium Ylides Synthesis from Aryl Diazoacetates and Sulfoxides, Chin. J. Chem. 2021, 39, 1646.

  14. Lei Li, Lili Fang, Jin Zhu*, Visible Light-Mediated Intermolecular Radical Conjugate Addition for the Construction of Vicinal All-Carbon Quaternary Centers, Org. Lett. 2020, 22, 5401.

  15. Lei Li, Shan Guo, Qi Wang, Jin Zhu*, Acyl Radicals from Benzothiazolines: Synthons for Alkylation, Alkenylation, and Alkynylation Reactions, Org. Lett. 2019, 21, 5462.