董惠钧，博士，教授，硕士研究生导师，执业药师，学术桥评审专家库成员，山东省重点扶持区域引进急需紧缺人才，聊城大学光岳英才。
教育背景
2003.09~2006.06 浙江大学，获博士学位
2000.09~2003.06 天津科技大学，获硕士学位
1996.09~2000.06 天津科技大学，获学士学位
工作经历
2024.07~ 聊城大学药学与食品工程学院
2013.01~2024.06 聊城大学药学院
2006.09~2012.12 鲁南制药集团股份有限公司
研究领域
(1) 医药、医美、化妆品和功能食品领域的生物活性物质合成生物学制造
(2) 药食同源、“三新食品”、药食用真菌与特医特膳等大健康产品的研究与开发
科研项目
（1）富含麦角硫因的功能性杏鲍菇人造肉研制，企业课题，2024-2026，项目负责人
（2）苯磺酸氨氯地平片剂的制备和一致性评价，企业课题，2023-2024，项目负责人
（3）具有抗病毒和增强免疫力双重功效的珍稀药用真菌功能健康产品的研究与开发，企业课题，2020-2022，项目负责人。
（4）健脾止遗颗粒剂的研制，企业课题，2018-2021，项目负责人。
（5）生物农药武夷菌素的分离纯化，企业课题，2014-2017，项目负责人。
近年发表论文
(1) Shi Shi, Yutong Cheng, Shuai Wang, Xiangmei Zhang, Fubo Han, Xiaojing Li, Huijun Dong. Improvement of the conjugation transfer of N. gerenzanensis based on the synergistic effect of quorum sensing and antibiotic interference. AMB Express, 2023, 13:133
(2) Li Tian, Bingyu Yan, Dandan Huo, Wenhui Sun, Sufang Cui, Shuai Wang, Huijun Dong*. Development and application of a modified CRISPR/Cas9 system with GusA reporter in the genome editing of N. gerenzanensis. Biotechnology Letters, 2023, 45: 401–410.
(3) Li Tian, Shi Shi, Xiangmei Zhang, Fubo Han, Huijun Dong*. Newest perspectives of glycopeptide antibiotics: biosynthetic cascades, novel derivatives, and new appealing antimicrobial applications. World J Microbiol Biotechnol., 2023, 39, 67
(4) Bingyu Yan, Wen Gao, Li Tian, Shuai Wang, Huijun Dong*. Production enhancement of the Glycopeptide Antibiotic A40926 by an engineered Nonomuraea gerenzanensis strain. Biotechnology Letters，2022，44:259-269.
(5) Wen Gao, Li Jin, Chunhong Liu, Ning Zhang, Ruiyan Zhang, Zuzana Bednarikova, Zuzana Gazova, Anirban Bhunia, Hans-Christian Siebert, Huijun Dong*. Inhibition behavior of Sennoside A and Sennoside C on amyloid fibrillation of human lysozyme and its possible mechanism. International Journal of Biological Macromolecules, 2021,178:424-433.
(6) Ning Zhang, Li Jin, Chunhong Liu, Ruiyan Zhang, Hans-Christian Siebert, Yanhui Li, Gabriele Loers, Athanasios K. Petridis, Zhangyong Xia, Huijun Dong, Xuexing Zheng. An antarctic krill oil-based diet elicits neuroprotective effects by inhibiting oxidative stress and rebalancing the M1/M2 microglia phenotype in a cuprizone model for demyelination. Journal of Functional Foods, 2021, 76:104309.
(7) Li Jin, Wen Gao, Chunhong Liu, Ning Zhang, Shruti Mukherjee, Ruiyan Zhang, Huijun Dong, Anirban Bhunia, Zuzana Bednarikova, Zuzana Gazova, Min Liu, Jun Han, Hans-Christian Siebert. Investigating the inhibitory effects of entacapone on amyloid fibril formation of human lysozyme. International Journal of Biological Macromolecules, 2020, 161:1393-1404.
(8) Huijun Dong*, Xue Yue, Bingyu Yan, Wen Gao, Shuai Wang, Yongquan Li. Improved A40926 production from Nonomuraea gerenzanensis using the promoter engineering and the co-expression of crucial genes. Journal of Biotechnology, 2020, 324:28-33.
(9) Xue Yue, Tianyu Xia, Shuai Wang, Huijun Dong*,Yongquan Li. Highly efficient genomic editing in N. gerenzanensis using an inducible CRISPR/Cas9/RecA system. Biotechnology Letters, 2020, 42:1699-1706.
(10) Xue Yue, Bingyu Yan, Shuai Wang, Wen Gao, Ruiyan Zhang, Huijun Dong*. Preparation of pH-responsive alginate–chitosan microspheres for L-Valine loading and their effects on the A40926 production. Current Microbiology, 2020, 77:1016-1023.
