硕士生导师简历

1. 
   基本信息                                      

姓名： 王世本

职称：副教授

学历： 博士

电子信箱：wangshiben110@163.com

出生年月：1986年11月

研究方向： 主要从事药理、药物化学相关科研工作。研究方向: 先导化合物的寻找与结构优化，中枢神经系统、抗炎药物等药理活性筛选及作用机制研究。

毕业学校： 延边大学

职务：

1. 研究工作简介

主持、参与国家级课题1项，省部级课题4项，主持校级课题3项，第一作者或通讯作者发表学科领域SCI论文十余篇，授权发明专利1项；2016年获吉林省科学技术奖三等奖（第三位）， 2020、2021年获聊城大学科学技术二等奖（首位），以第一指导教师指导本科生参加各类省、校级学生竞赛并获奖多项。

1. 发表论文（按时间倒序排列）

[1] Xuekun Wang, Hao Zhou, Xinyu Wang, Kang Lei and Shiben Wang*. Design, Synthesis, and In Vivo and In Silico Evaluation of Coumarin Derivatives with Potential Antidepressant Effects. Molecules 2021, 26, 5556. (SCI 3区)

[2] Shiben Wang*, Hui Liu, Xuekun Wang, Kang Lei, Guangyong Li, Jun Li, Renmin Liu, Zheshan Quan*. Synthesis of 1,3,4-oxadiazole derivatives with anticonvulsant activity and their binding to the GABAA receptor. European Journal of Medicinal Chemistry 2020, 206, 112672. (SCI 1区)

[3] Shiben Wang*, Hui Liu, Kang Lei, Guangyong Li, Jun Li, Yuyu Wei, Xuekun Wang, Renmin Liu*. Synthesis of 3,4-dihydroquinolin-2(1H)-one derivatives with anticonvulsant activity and their binding to the GABAA receptor. Bioorganic Chemistry 2020, 103, 104182. (SCI 1区)

[4] Shiben Wang*, Lin Qi, Hui Liu, Kang Lei, Xuekun Wang, Renmin Liu*. Synthesis of 1,3,4-oxadiazoles derivatives with antidepressant activity and their binding to the 5-HT1A receptor. RSC Advances 2020, 10, 30848. (SCI 3区)

[5] Shiben Wang*, Hui Liu, Guangyong Li, Jun Li, Xiaojing Li, Kang Lei, Lichao Wei, Zheshan Quan, Xuekun Wang, Renmin Liu*. Pharmacological Reports 2019, 71, 1244–1252. (SCI 3区)

[6] Shiben Wang*, Hui Liu, Xuekun Wang, Kang Lei, Guangyong Li, Zheshan Quan. Synthesis and Evaluation of Antidepressant Activities of 5-Aryl-4,5-dihydrotetrazolo[1,5-a]thieno[2,3-e]pyridine Derivatives. Molecules 2019, 24, 1857. (SCI 3区)

[7] Shiben Wang*, Hui Liu, Xuekun Wang, Kang Lei, Guangyong Li, Xiaojing Li, Lichao Wei, Zheshan Quan. Synthesis and evaluation of anticonvulsant activities of 7-phenyl-4,5,6,7-tetrahydrothieno[3,2-b]pyridine Derivatives. Archiv der Pharmazie 2019, 352:1900106. (SCI 4区)

[8] Qingkun Shen, Hao Deng, Shiben Wang, Yushun Tian, Zheshan Quan. Synthesis,and evaluation of in vitro and in vivo anticancer activity of14-substituted oridonin analogs: A novel and potent cell cycle arrestand apoptosis inducer through the p53-MDM2 pathway. European Journal of Medicinal Chemistry 173 (2019) 15-31. (SCI 1区)

[9] Mingxia Song, Shiben Wang, Zengtao Wang, Zhiyang Fu, Shengchao Zhou, Huabin Cheng, Zhuo Liang, Xianqing Deng. Syntheis,antimicrobial and cytotoxic activities, and moleculardocking studies of N-arylsulfonylindoles containing anaminoguanidine, a semicarbazide, and a thiosemicarbazide moiety. European Journal of Medicinal Chemistry 166 (2019) 108-118. (SCI 1区)